new mirtazipine

[Vikki]

Hi

My doc has just suggested i try a new form of mirtazipine, it comes on rice paper and dissolves instantly on the tongue.

Has anyone any experience of this?

worth a go, i decided the st johns wort wouldn't work as it had many ingrdients of tablets, and I didn't want to risk an outbreak of my skin when it is nearing normality again.

Thankjs tonnes

Vikki

[Jane]

Hi Vikki,
Just wanted to say that I've taken quite alot of different medications over the years but never heard of that one babe.
Sounds better than a traditional tablet by melting on the tongue. Is it an anti d or something else hun?
Love Jane x

[Vonda]

Hi Vikki

I have not heard of this one either. I like the sound of one that melts on your tongue - but only if it has a nice flavour!

Vonda

[Veritee]

Hi Vikki

I recently was given a woman to support by phone by the Association of Post Natal Illness who is on Mirtazipine and I have to admit it is a new one on me so I have done my best to find out about it.

See this link for a page specifically on the type of dissolving tablet you are on:
www.medicinenet.com/mirtazapine_disintegrating_tablets-oral/article.htm

This is a US page I could not find a good UK site for the information.

This is what I have found out so far:

It is a newish drug but derived from a very old type of anti depressant ( indeed of the type I was prescribed as a depressed 17 year old - it is a tetracyclic antidepressant.

the precise mechanism of action of this class of antidepressants is not known, they increase the amount of noradrenalin and serotonin in the brain. Noradrenaline and serotonin are neurotransmitters, chemicals that nerves use to communicate with each other.

Mirtazapine also acts as an antihistamine similar to diphenhydramine (Benadryl).

Antihistamines make you drowsy.


I think your doctor is trying this because all the other Anti Ds you have been on have been of the newer SSRI, ( selective serotonin reuptake inhibitors) type and some people just do not get on with these so then they try the older AntiDs - either tetracyclic, Tricyclic or MAOs Anti Ds ( I also had these when I was young.

Mirtazapine specifically was approved by the FDA in 1996. Thi sis they US I can nto find out when it was approved in the UK.

in the US where it has been used longer it is called Remeron, does you packet have a brand name on it??


I think at the end of the day it does not mater what it is, so much as whether it works for you.

It cold be you are someone who does not respond well to the SSRIs such as Prozac

Some stuff writen about the r=effectiveness and side effects:

In US controlled clinical trials of 6-week duration, the most commonly reported adverse events associated with REMERON® (mirtazapine) Tablets therapy were: somnolence ie sleepyness (54%), increased appetite (17%), weight gain (12%), and dizziness (7%). In short-term clinical trials, 10.4 % of patients discontinued therapy due to somnolence. In a pool of premarketing US studies, including patients in long-term, open-label treatment, 8% of patients discontinued therapy due to weight gain.

Patients, their families, and their caregivers should be encouraged to be alert to the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation, especially early during antidepressant treatment and when the dose is adjusted up or down.

Anyway this is what I know so far but really your GP would not have given them to you if they were not worth trying so give them a go and see how you feel in a couple of weeks.

Medication is not a cure for PNI but is can help you deal with the effects and lift your mood so that you can have time to recover.

I will get back to you when I know more

All the best

[Vikki]

Thanks for all your posts, I have taken Mirtazipine in a tablet form before but due the allergic reaction, i wasn't able to give it long enough to work, i quite liked it tho, cos i suffer with quite bad insomnia, and these really helped me sleep.

Fingers crossed, I let you know how I got on with it.

[rach]

hi

i have also been given mirtazipine by my phyc
i fould it great it helped with my energy levels moods and for the 4 weeks i was on i didn't have a bad day!

however unfort for me i put on a stone in that 4 weeks and found that i was starving all the time sometimes i was painfully hungery, the strangest thing was i woiuld have eaten and been stuffed but still have hunger pains ??

i hope it works for you.

do you know if the disolve has diff side effects!

i am on lustral now ok but not great.

love rach

[AUSSIE GIRL]

Hi I had mirtazapine i foud it helped me to sleep but thats about it so changed meds, i took it in tablet form.
Tracey

[marion]

I normally take mirtazapine in the oral disperable form that disolves on your tongue. I had my dose upped this month and this is the first time my dr has dispensed this higher dose to me and he's written the presciption up (which I've just picked up from the chemist) in the non disolvable tablet form. Does this make any difference to the drug or is it like soluble asprin and tablet asprin- it's the same stuff just doesnt disolve?

Bit worried. Sure it's the same but just wondered if anyone new.
Thanks
Marion.